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SamoneLenior View Drop Down
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Post Options Post Options   Thanks (2) Thanks(2)   Quote SamoneLenior Quote  Post ReplyReply Direct Link To This Post Posted: Jan 31 2013 at 12:01pm

yall disputing science?

MRI studies of the brain show that developmental processes tend to occur in the brain in a back to front pattern, explaining why the prefrontal cortex develops last. These studies have also found that teens have less white matter (myelin) in the frontal lobes of their brains when compared to adults, but this amount increases as the teen ages. With more myelin comes the growth of important brain connections, allowing for better flow of information between brain regions.
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gabi03 View Drop Down
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Post Options Post Options   Thanks (8) Thanks(8)   Quote gabi03 Quote  Post ReplyReply Direct Link To This Post Posted: Jan 31 2013 at 12:05pm
^^^ you know bhm and science don't go together.
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Naturalchick30 View Drop Down
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Post Options Post Options   Thanks (0) Thanks(0)   Quote Naturalchick30 Quote  Post ReplyReply Direct Link To This Post Posted: Jan 31 2013 at 12:06pm
Originally posted by Lady ICE Lady ICE wrote:

Originally posted by melikey melikey wrote:

No I'm pretty much the same except less tolerant .. i
used to entertain foolishness far too long.
Now ain't nobody got time for that! Lol
this all day.
 
yup
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Post Options Post Options   Thanks (0) Thanks(0)   Quote nitabug Quote  Post ReplyReply Direct Link To This Post Posted: Jan 31 2013 at 12:07pm
yes
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maysay1 View Drop Down
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Post Options Post Options   Thanks (0) Thanks(0)   Quote maysay1 Quote  Post ReplyReply Direct Link To This Post Posted: Jan 31 2013 at 12:34pm
I definitely agree...science says so...dr. drew says so (dr drew is my life coach)...and my experiences say so.

I would like to find out more about how drug use (especially alcohol and weed) in the early years affects that prefrontal cortex development.


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SamoneLenior View Drop Down
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Post Options Post Options   Thanks (0) Thanks(0)   Quote SamoneLenior Quote  Post ReplyReply Direct Link To This Post Posted: Jan 31 2013 at 12:37pm

Marijuana Use Takes Toll On Adolescent Brain Function, Research Finds

Oct. 15, 2008 — Brain imaging shows that the brains of teens that use marijuana are working harder than the brains of their peers who abstain from the drug.


At the 2008 annual meeting of the American Academy of Pediatrics in Boston, Mass., Krista Lisdahl Medina, a University of Cincinnati assistant professor of psychology, presented collaborative research with Susan Tapert, associate professor of psychiatry at the University of California, San Diego.

Medina’s Oct. 12 presentation, titled, “Neuroimaging Marijuana Use and its Effects on Cognitive Function,” suggests that chronic, heavy marijuana use during adolescence – a critical period of ongoing brain development – is associated with poorer performance on thinking tasks, including slower psychomotor speed and poorer complex attention, verbal memory and planning ability. Medina says that’s evident even after a month of stopping marijuana use. She says that while recent findings suggest partial recovery of verbal memory functioning within the first three weeks of adolescent abstinence from marijuana, complex attention skills continue to be affected.

“Not only are their thinking abilities worse, their brain activation to cognitive tasks is abnormal. The tasks are fairly easy, such as remembering the location of objects, and they may be able to complete the tasks, but what we see is that adolescent marijuana users are using more of their parietal and frontal cortices to complete the tasks. Their brain is working harder than it should,” Medina says.

She adds that recent findings suggest females may be at increased risk for the neurocognitive consequences of marijuana use during adolescence, as studies found that teenage girls had marginally larger prefrontal cortex (PFC) volumes compared to girls who did not smoke marijuana. The larger PFC volumes were associated with poorer executive functions of the brain in these teens, such as planning, decision-making or staying focused on a task.

Medina says adolescence is a critical time of brain development and that the findings are yet another warning for adolescents who experiment with drug use. She says more study is needed to see if the thinking abilities of adolescent marijuana users improve following longer periods of abstinence from the drug. “Longitudinal studies following youth over time are needed to rule out the influence of pre-existing differences before teens begin using marijuana, and to examine whether abstinence from marijuana results in recovery of cognitive and brain functioning,” says Medina.

The research was supported by the National Institute on Drug Abuse (NIDA).


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SamoneLenior View Drop Down
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Post Options Post Options   Thanks (0) Thanks(0)   Quote SamoneLenior Quote  Post ReplyReply Direct Link To This Post Posted: Jan 31 2013 at 12:41pm

Increased Marijuana Use and Gender Predict Poorer Cognitive Functioning in Adolescents and Emerging Adults

Krista M. Lisdahla1a2 c1 and Jenessa S. Pricea3

a1 Department of Psychology, University of Wisconsin-Milwaukee, Milwaukee, Wisconsin

a2 Clinical & Translational Science Institute, Medical College of Wisconsin, Milwaukee, Wisconsin

a3 Department of Psychology, University of Cincinnati, Cincinnati, Ohio

Abstract

This study sought to characterize neuropsychological functioning in MJ-using adolescents and emerging adults (ages 18–26) and to investigate whether gender moderated these effects. Data were collected from 59 teens and emerging adults including MJ users (n = 23, 56% female) and controls (n = 35, 50% female) aged 18–26 (M = 21 years). Exclusionary criteria included independent Axis I disorders (besides SUD), and medical and neurologic disorders. After controlling for reading ability, gender, subclinical depressive symptoms, body mass index, and alcohol and other drug use, increased MJ use was associated with slower psychomotor speed/sequencing ability (p < .01), less efficient sustained attention (p < .05), and increased cognitive inhibition errors (p < .03). Gender significantly moderated the effects of MJ on psychomotor speed/sequencing ability (p < .003) in that males had a more robust negative relationship. The current study demonstrated that MJ exposure was associated with poorer psychomotor speed, sustained attention and cognitive inhibition in a dose-dependent manner in young adults, findings that are consistent with other samples of adolescent MJ users. Male MJ users demonstrated greater cognitive slowing than females. Future studies need to examine the neural substrates underlying with these cognitive deficits and whether cognitive rehabilitation or exercise interventions may serve as a viable treatments of cognitive deficits in emerging adult MJ users. (JINS, 2012, 18, 1–11)


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SamoneLenior View Drop Down
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Post Options Post Options   Thanks (0) Thanks(0)   Quote SamoneLenior Quote  Post ReplyReply Direct Link To This Post Posted: Jan 31 2013 at 12:42pm

Longitudinal Changes in White Matter Integrity Among Adolescent Substance Users

  1. Sunita Bava1,2,
  2. Joanna Jacobus1,2,
  3. Rachel E. Thayer3,
  4. Susan F. Tapert1,2,*

Article first published online: 14 DEC 2012

DOI: 10.1111/j.1530-0277.2012.01920.x

Background

The influence of repeated substance use during adolescent neurodevelopment remains unclear as there have been few prospective investigations. The aims of this study were to identify longitudinal changes in fiber tract integrity associated with alcohol- and marijuana-use severity over the course of 1.5 years.

Methods

Adolescents with extensive marijuana- and alcohol-use histories by mid-adolescence (= 41) and youth with consistently minimal if any substance use (= 51) were followed over 18 months. Teens received diffusion tensor imaging and detailed substance-use assessments with toxicology screening at baseline and 18-month follow-ups (i.e., 182 scans in all), as well as interim substance-use interviews each 6 months.

Results

At an 18-month follow-up, substance users showed poorer white matter integrity in 7 tracts: (i) right superior longitudinal fasciculus, (ii) left superior longitudinal fasciculus, (iii) right posterior thalamic radiations, (iv) right prefrontal thalamic fibers, (v) right superior temporal gyrus white matter, (vi) right inferior longitudinal fasciculus, and (vii) left posterior corona radiata (ps < 0.01). More alcohol use during the interscan interval predicted higher mean diffusivity (i.e., worsened integrity) in right (< 0.05) and left (= 0.06) superior longitudinal fasciculi, above and beyond baseline values in these bundles. Marijuana use during the interscan interval did not predict change over time. More externalizing behaviors at Time 1 predicted lower fractional anisotropy and higher radial diffusivity (i.e., poorer integrity) of the right prefrontal thalamic fibers (< 0.025).

Conclusions

Findings add to previous cross-sectional studies reporting white matter disadvantages in youth with substance-use histories. In particular, alcohol use during adolescent neurodevelopment may be linked to reductions in white matter quality in association fiber tracts with frontal connections. In contrast, youth who engage in a variety of risk-taking behaviors may have unique neurodevelopmental trajectories characterized by truncated development in fronto-thalamic tracts, which could have functional and clinical consequences in young adulthood.


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maysay1 View Drop Down
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Post Options Post Options   Thanks (1) Thanks(1)   Quote maysay1 Quote  Post ReplyReply Direct Link To This Post Posted: Jan 31 2013 at 12:46pm
Thanks Samone!

That confirmed what I suspected. I worry for my students because a lot of them start drinking and smoking weed at least once or twice a week starting in middle school. The long-term effects on their brain function are going to be devastating...just looking at their parents it's obvious.

How do you deal with generations of people who can't learn/reason/etc?
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SamoneLenior View Drop Down
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Post Options Post Options   Thanks (0) Thanks(0)   Quote SamoneLenior Quote  Post ReplyReply Direct Link To This Post Posted: Jan 31 2013 at 12:50pm
Originally posted by maysay1 maysay1 wrote:

Thanks Samone!

That confirmed what I suspected. I worry for my students because a lot of them start drinking and smoking weed at least once or twice a week starting in middle school. The long-term effects on their brain function are going to be devastating...just looking at their parents it's obvious.

How do you deal with generations of people who can't learn/reason/etc?


though weed is reported to negatively impact development, there are a lot of former pot heads that are now successful members of our society

now of course their environment, peer group, and family play a major role as well...which leads to the second part of your post

idk the answer for that question
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